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Intra Cytoplasmic Sperm Injection (ICSI)

ICSI – Intra Cytoplasmic Sperm Injection Treatment

The head of the sperm must adhere to the outside of the egg before it may fertilise a woman’s egg. Once connected, the sperm pushes through the egg’s cytoplasm to the interior, where fertilisation occurs.

For a variety of reasons, the sperm occasionally cannot penetrate the outer layer. The sperm may not be able to swim or the egg’s outer layer may be thick or difficult to penetrate. In certain situations, intracytoplasmic sperm injection, often known as ICSI, can be used in conjunction with in vitro fertilisation (IVF) to assist in fertilising the egg. A single sperm is injected directly into the cytoplasm of the egg during ICSI.

How does ICSI work?

IVF allows for both standard and ICSI fertilisation of an egg. In a laboratory dish, the egg is placed close to 50,000 or more swimming sperm during classical IVF. When one of the sperm enters the cytoplasm of the egg, fertilisation takes place. In the ICSI procedure, a single sperm is injected into the centre of the egg using a tiny needle called a micropipette. After fertilisation, whether via traditional IVF or ICSI, the fertilised egg (now known as an embryo) develops in a lab for one to five days before being implanted into the woman’s uterus (womb).

Why would I need ICSI?

ICSI helps to overcome fertility problems, such as:

  • IUI or IVF cannot be performed because the male partner’s sperm production is insufficient.
  • It’s possible that the sperm do not migrate normally.
  • It could be challenging for the sperm to adhere to the egg.
  • Sperm may not be able to exit the male reproductive canal if there is a blockage.
  • Regardless of the sperm’s health, traditional IVF has not been successful in fertilising eggs.
  • The eggs are in vitro matured.
  • Eggs that had been frozen before are being used.

Will ICSI work?

ICSI fertilizes 50% to 80% of eggs. But the following problems may occur during or after the ICSI process:

  • The eggs could be harmed in part or totality.
  • Even after the sperm is inserted into the egg, the egg may not develop into an embryo.
  • The embryo can halt developing.
Once fertilisation has occurred, a couple’s likelihood of having a single child, twins, or triplets is identical whether they undergo IVF with or without ICSI.

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